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non tumorigenic mcf10a control breast cell line  (ATCC)


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    Structured Review

    ATCC non tumorigenic mcf10a control breast cell line
    Non Tumorigenic Mcf10a Control Breast Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 8168 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/non+tumorigenic+mcf10a+control+breast+cell+line/MCF+10A/pm38945837-153-2-11
    Average 99 stars, based on 8168 article reviews
    non tumorigenic mcf10a control breast cell line - by Bioz Stars, 2026-10
    99/100 stars

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    Related Articles

    Multiple Displacement Amplification:

    Article Title: Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.
    Article Snippet: Mitochondria in tumor cells are functionally different from those in normal cells and could be targeted to develop new anticancer agents.. We showed recently that the aryl-ureido fatty acid CTU is the prototype of a new class of mitochondrion-targeted agents that kill cancer cells by increasing the production of reactive oxygen species (ROS), activating endoplasmic reticulum (ER)-stress and promoting apoptosis.. However, prolonged treatment with high doses of CTU were required for in vivo anti-tumor activity.

    Article Title: The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism.
    Article Snippet: The cancer cell mitochondrion is functionally different from that in normal cells and could be targeted to develop novel experimental therapeutics.. The aryl-ureido fatty acid CTU (16({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)hexadecanoic acid) is the prototype of a new class of mitochondrion-targeted agents that kill cancer cells.. Here we show that CTU rapidly depolarized the inner mitochondrial membrane, selectively inhibited complex III of the electron transport chain and increased reactive oxygen species (ROS) production.

    Control:

    Article Title: Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.
    Article Snippet: Mitochondria in tumor cells are functionally different from those in normal cells and could be targeted to develop new anticancer agents.. We showed recently that the aryl-ureido fatty acid CTU is the prototype of a new class of mitochondrion-targeted agents that kill cancer cells by increasing the production of reactive oxygen species (ROS), activating endoplasmic reticulum (ER)-stress and promoting apoptosis.. However, prolonged treatment with high doses of CTU were required for in vivo anti-tumor activity.

    Article Title: Carbon chain length in a novel anticancer aryl-urea fatty acid modulates mitochondrial targeting, reactive oxygen species production and cell killing.
    Article Snippet: The cancer cell mitochondrion could be a promising target for the development of new anticancer agents.. 16-([3-chloro-5-(trifluoromethyl)phenyl]carbamoylamino)hexadecanoic acid (2) is a novel aryl-urea fatty acid that targets the mitochondrion in MDA-MB-231 breast cancer cells and activates cell death.. In the present study, the relationships between alkyl chain length in 2 analogues, mitochondrial disruption and cell killing were evaluated.

    Article Title: The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism.
    Article Snippet: The cancer cell mitochondrion is functionally different from that in normal cells and could be targeted to develop novel experimental therapeutics.. The aryl-ureido fatty acid CTU (16({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)hexadecanoic acid) is the prototype of a new class of mitochondrion-targeted agents that kill cancer cells.. Here we show that CTU rapidly depolarized the inner mitochondrial membrane, selectively inhibited complex III of the electron transport chain and increased reactive oxygen species (ROS) production.



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    99
    ATCC non tumorigenic mcf10a control breast cell line
    Non Tumorigenic Mcf10a Control Breast Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/non+tumorigenic+mcf10a+control+breast+cell+line/MCF+10A/pm38945837-153-2-11
    Average 99 stars, based on 1 article reviews
    non tumorigenic mcf10a control breast cell line - by Bioz Stars, 2026-10
    99/100 stars
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